ISSN : 2488-8648
International Journal of Basic Science and Technology
A publication of the Faculty of Science, Federal University Otuoke, Bayelsa State
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ISSN : 2488-8648
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×published date:2016-Dec-16
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| page 46-49
Abstract
The effects of the plant Ocimum gratissimum was assessed on some hematological parameters including white blood cell (WBC) indices, packed cell volume (PCV), hemoglobin (Hb) and platelet count and cell-mediated aspect of immunity (CD4 count and secretion of 1nterleukin-2) on rabbits after a repeated administration of the plant additive at different doses for a period of eight (8) weeks were determined. The results showed a significant increase (P < 0.05) in all the hematological parameters studied in a dose dependent manner. The results obtained also showed that O. gratissimum - supplemented diet caused a significant increase (P < 0.05) in the CD4 count and secretion of interleukin-2 which is a hematopoietin; hence enhancing immune response.
Keywords: CD4 count, cell-mediated immunity, hematological parameters, interleukin 2, Ocimum grat
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