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International Journal of Basic Science and Technology

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Archive | ISSUE: , Volume: Apr-Jun-2024

Antibacterial Efficacy of Coconut Oil Against Specific Isolates


Author:Anyiam, I.V.; Opara, C.N.

published date:2024-May-02

FULL TEXT in - | page 119 -124

Abstract

Phytochemical analysis and antibacterial activities of the coconut oil against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Klebsiella spp were determined using microbiological standard and disc diffusion methods .Qualitative phytochemical analysis showed the presence of flavonoids, tannins, phenols, anthocyanins, terpenoids, and alkaloids. Quantitative phytochemical analysis revealed total phenolic and total flavonoid constituents as 0.822 ± 0.011 GAE/mg and 19.83 ± 1.69 GAE/mg, respectively. Significant dose-dependent DPPH (2, 2-Diphenyl-1-picrylhydrazyl) radical scavenging ability was demonstrated by the coconut oil. At 125 μg/ml, it inhibited 91.01 ± 1.53 percent of DPPH, while ascorbic acid inhibited 94.18 ± 3.22 percent at the same dose. Against every test organism, the coconut oil exhibited strong antibacterial activity (p<0.05). In contrast, the coconut oil's zone of inhibition against the test microorganisms revealed the biggest zone of inhibition—22 mm and 13 mm, respectively when tested against Staphylococcus aureus at concentrations of 40 mg/ml and 20 mg/ml. In contrast, the lowest was 2 mm at a 20 mg/ml concentration when it came to Klebsiella species. The results of this study showed that coconut oil possesses antibacterial properties that could be used to create novel antimicrobials to treat infections and other illnesses, as well as to fight antibiotic resistance

Keywords: Phytochemical analysis; Antibacterial activity; Zone of inhibition; Coconut oil,,,,

References

Abbas, A. A., Peter, U., Akeh, M., Adeola, J., Ewenighi C. O. and Ishaku, A. (2017). Antibacterial Activity of Lauric Acid on Some Selected Clinical Isolates. Annals of Clinical and Laboratory Research (10). 2386-5180.

Anyiam, I.V and Mounmbegna, P.P.E. (2020). Free radical scavenging potential and antibacterial activity of Cola nitida and Garcinia kola extracts against bacterial strains isolated from patients with urinary tract infections. Ruhuna Journal of Science 11 (2): 98-117.

Bandeira, P. N., Fonseca, A. M., Costa S. M. O., Lins M. U. D. S., Pessoa, O. D.L., Monte, F. J. Q., Nogueira, N. A. P and Lemos, T. L. G. (2006). Antimicrobial and antioxidant activities of the essential oil of resin of Protium heptaphyllum. Nat Prod Commun (1) 117-120.

Barreira, J., Ferreira, I., Oliveira, M, and Pereira, J. (2008). Antioxidant activity and bioactive compounds of ten Portuguese regional and commercial almond cultivars. Food Chemistry and Toxicology (46) 2230–2235.

Carpo, B. G., Verallo-Rowell, V. M and Kabara, J. (2007). Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study. Journal of Drugs Dermatology 6(10):991-8.

Cheesbrough, M. (2006). District Laboratory Practice in Tropical Countries Part 1, (2nd Ed). New York: Cambridge University Press. Pp: 38-39.

Clarke, N. M and May, J. T. (2000). Effect of antimicrobial factors in human milk on rhinoviruses and milk-borne cytomegalovirus in vitro. Journal of Medical Microbiology 49(8)719-723

Ekpo, M.A and Etim, P.C., (2009). Antimicrobial activity of ethanolic and aqueous extracts of Sida acuta on microorganisms from skin infections. Journal of Medicinal Plants Research. 3(9): 621-624

Ezeigbo, O. R., Awomukwu, D. A and Ezeigbo, IC (2016). The antimicrobial and phytochemical analysis of the leaves of Aspilia africana on clinical isolates. European Journal of Medical Plants 15:1-6.

Floriana, S. L., Jansen, S and Duri, S. (2015). Antibacterial activity of enzymatic hydrolysed virgin coconut oil and palm kanel oil against Staphyloccocus aureus, Salmonella typhi and E. coli. International Journals of pharmaceutical Technology and research, 6(2): 628-633.

Fowoyo P, and Alamu J (2018). Nutritional composition and antimicrobial acidity of coconut water against selected gastrointestinal pathogens. International Journal of Microbiology and Application 5(1):1-8.

Manisha, D and Shyamapada, D (2011). Coconut (Cocos nucifera L; Arecaceae): In health promotion and disease prevention, Asian pacific journal of tropical medicine. 4(3)241-247

Nasimuddin, S., Durai. R and Sumathi, G. (2016). A study of invitro antimicrobial activity of coconut water and coconut oil on gram positive and gram negative bacteria. World Journal of Pharmaceutical Resource 5(8):696-700

Nevin, K.G and Rajamohan, T. (2004).Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation. Clinical Biochemistry, 37, 830-835.

Odinakachukwu, P.O., Okechukwu, J.  O., Ibuchukwu Orabueze, N. A and Anthony C. I (2019). Antibacterial activity of leaf extract of Chromolaena odorata and the effect of its combination with some conventional antibiotics on Pseudomonas aeruginosa isolated from wounds. Journal of Applied Biology & Biotechnology. 7(03), pp. 36-40.

Ogbolu, D. O., Oni, A. A., Daini, O. A and Oloko, A. P. (2007). In Vitro Antimicrobial Properties of Coconut Oil on Candida Species. Journal of Medicinal Food. (10)2:384–387.

Owoyale, J. A., Olatunji, G. A and Oguntoye, S. O. (2005). Antifungal and antibacterial activities of an ethanolic extract of Senna alata leaves. Journal of applied science and environmenal Management. (9) 105-107.

Pires, M., Costa, R. S., Jose, A. S., Badaro, M. M., Midlej, C, and Alves, J. M. (2004). The coconut culture: an economical evaluation. Rev. Bras Friutic., 26 (1): 173-176.

Shanmugan, H.; Anil, K.; Mukesh, D. (2008).Synergism between natural products and antibiotics against infectious diseases. Journal of Phytomedical, 1(5) 639-652.

Taiwo, A. A., Omobola, O. O, David, A. A and Anthony, I. O. (2011) In-Vitro Antibacterial Properties of Crude Aqueous and n-Hexane Extracts of the Husk of Cocos nucifera: Molecules. (16): 2135-2145.

WHO, 2003. Background document: The diagnosis, treatment, and prevention of typhoid fever. Communicable Disease Surveillance and Response Vaccines and Biologicals, Department of Vaccines and Biologicals CH- 1211 Geneva 27, Switzerland. pp 7-11.

 

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